@ARTICLE{Markiewicz_W._Influence_2018, author={Markiewicz, W. and Wiśniewska, A. and Madej-Śmiechowska, H. and Burmańczuk, A. and Jaroszewski, J.J.}, volume={vol. 21}, number={No 4}, journal={Polish Journal of Veterinary Sciences}, pages={823-825}, howpublished={online}, year={2018}, publisher={Polish Academy of Sciences Committee of Veterinary Sciences}, publisher={University of Warmia and Mazury in Olsztyn}, abstract={This study analysed the influence of montelukast (MON; 10-8 - 10-4 M), a cysteinyl leukotriene receptor 1 (CysLTR1) antagonist, on the contractility of the porcine uterine smooth muscle in the luteal phase of the oesterous cycle (n=8) and in early pregnancy (n=8). Stimulation of uterine strips in the luteal phase with MON has been shown to significantly reduce the amplitude of con- tractions, but not to affect the tension or frequency of contractions. A statistically significant tension increase and decrease in the frequency and amplitude of contractions was observed in pigs in early pregnancy. This suggests that MON has a different effect on the parameters under study in cyclic and pregnant pigs.}, type={Short communication}, title={Influence of leukotriene receptor antagonist on contractile activity of the porcine uterines mooth muscle in the luteal phase and in early pregnancy}, URL={http://www.journals.pan.pl/Content/109587/PDF/23.pdf}, doi={10.24425/pjvs.2018.125595}, keywords={montelukast, cyclic pigs, early pregnancy, uterine contractility}, }