TY - JOUR N2 - The aim was to explore the feasibility of using bamboo vinegar powder as an antibiotics substitute in weaning piglets. Forty-five healthy Duroc × Landrance × Yorshire piglets (weight 6.74 ± 0.17 kg; age 31 days) were randomly divided into the control group (basic diet), ANT group (basic diet + 0.12% compound antibiotics), BV1 group (basic diet + 0.1% bamboo vinegar powder), BV5 group (basic diet + 0.5% bamboo vinegar powder) and BV10 group (basic diet + 1% bamboo vinegar powder). MyD88 and CD14 expression in immune tissues was examined using real-time PCR. MyD88 expression in the control group were significantly lower than that in other groups in all tissues (p<0.05), while CD14 expression showed the opposite trend. MyD88 expression was significantly higher in the BV10 group than in other groups in lung tissue (P<0.05), significantly higher in the ANT group than in the BV1 group in the kidneys (P<0.05), significantly higher in the BV10 group than in the BV1 group in the thymus (P<0.05), and signifi- cantly higher in the BV1 group than in the BV10 group in the lymphatic tissue (P<0.05). These differences between experimental groups were not observed for the CD14 gene (P>0.05). Thus, adding bamboo vinegar powder to the basic diet of weaning piglets had immune effects similar to antibiotics and the effect was dose-dependent. Moreover, the MyD88 and CD14 genes appear to play a role in these immune effects L1 - http://www.journals.pan.pl/Content/108440/PDF/14.pdf L2 - http://www.journals.pan.pl/Content/108440 PY - 2018 IS - No 3 EP - 525–532 DO - 10.24425/124286 KW - bamboo vinegar powder KW - pig KW - antibiotics KW - MyD88 gene KW - CD14 gene A1 - Qin, W.Y. A1 - Gan, L.N. A1 - Dong, L. A1 - Yu, L.H. A1 - Wu, S.L. A1 - Bao, W.B. PB - Polish Academy of Sciences Committee of Veterinary Sciences PB - University of Warmia and Mazury in Olsztyn VL - vol. 21 DA - 2018.11.20 T1 - Effect of bamboo vinegar powder on the expression of the immune-related genes MyD88 and CD14 in weaning piglets SP - 525–532 UR - http://www.journals.pan.pl/dlibra/publication/edition/108440 T2 - Polish Journal of Veterinary Sciences ER -