TY - JOUR N2 - The aim of our study was to determine the influence of L-carnitine (L-CAR) on the cellular parameters of hen erythrocytes during a 48 hour exposure to L-CAR at concentrations of 25, 50 and 100 mg/mL in nutrient-deficient medium. Cell morphology, haemolysis, caspase 3/7 activity and glucose uptake (GU) were determined. The results showed a lower percentage of apoptotic cells and decreased haemolysis of erythrocytes treated for 48 hours at all the concentrations of L-CAR. The amino acid at 50 mg/mL inhibited the activity of proapoptotic caspase 3/7; however, it increased GU. In contrast, caspase 3/7 level was increased but GU was decreased in erythrocytes treated with 100 mg/mL of L-CAR when compared to the control. It may be hypothesized that reduction of apoptotic changes in hen erythrocytes may result from increased GU. L1 - http://www.journals.pan.pl/Content/109584/PDF/20.pdf L2 - http://www.journals.pan.pl/Content/109584 PY - 2018 IS - No 4 EP - 811–813 DO - 10.24425/pjvs.2018.125592 KW - L-carnitine KW - erythrocyte morphology KW - caspase 3/7 KW - hemolysis KW - apoptosis A1 - Kasperek, K. A1 - Bownik, A. A1 - Knaga, S. A1 - Szabelak, A. A1 - Ślaska, B. A1 - Kwiecień, M. A1 - Jeżewska-Witkowska, G. PB - Polish Academy of Sciences Committee of Veterinary Sciences PB - University of Warmia and Mazury in Olsztyn VL - vol. 21 DA - 2018.12.20 T1 - Effects of L-carnitine on morphology and cellular parameters of hen erythrocytes SP - 811–813 UR - http://www.journals.pan.pl/dlibra/publication/edition/109584 T2 - Polish Journal of Veterinary Sciences ER -