TY - JOUR N2 - In this paper the authors propose a decision support system for automatic blood smear analysis based on microscopic images. The images are pre-processed in order to remove irrelevant elements and to enhance the most important ones – the healthy blood cells (erythrocytes) and the pathologic ones (echinocytes). The separated blood cells are analysed in terms of their most important features by the eigenfaces method. The features are the basis for designing the neural network classifier, learned to distinguish between erythrocytes and echinocytes. As the result, the proposed system is able to analyse the smear blood images in a fully automatic way and to deliver information on the number and statistics of the red blood cells, both healthy and pathologic. The system was examined in two case studies, involving the canine and human blood, and then consulted with the experienced medicine specialists. The accuracy of classification of red blood cells into erythrocytes and echinocytes reaches 96%. L1 - http://www.journals.pan.pl/Content/110236/PDF/art_08.pdf L2 - http://www.journals.pan.pl/Content/110236 PY - 2019 IS - No 1 EP - 93 DO - 10.24425/mms.2019.126323 KW - optical microscopy KW - blood cells KW - biophotonics KW - image analysis KW - classification KW - eigenfaces KW - neural networks KW - decision support KW - nanodiamonds KW - bioimaging A1 - Grochowski, Michał A1 - Wąsowicz, Michał A1 - Mikołajczyk, Agnieszka A1 - Ficek, Mateusz A1 - Kulka, Marek PB - Polish Academy of Sciences Committee on Metrology and Scientific Instrumentation VL - vol. 26 DA - 2019.04.01 T1 - Machine learning system for automated blood smear analysis SP - 81 UR - http://www.journals.pan.pl/dlibra/publication/edition/110236 T2 - Metrology and Measurement Systems ER -