TY - JOUR N2 - Resonance assignment remains one of the hardest stages in RNA tertiary structure determination with the use of Nuclear Magnetic Resonance spectroscopy. We propose an evolutionary algorithm being a tool for an automatization of the procedure. NOE pathway, which determines the assignments, is constructed during an analysis of possible connections between resonances within aromatic and anomeric region of 2D-NOESY spectra resulting from appropriate NMR experiments. Computational tests demonstrate the performance of the evolutionary algorithm as compared with the exact branch-and-cut procedure applied for the experimental and simulated spectral data for RNA molecules. L1 - http://www.journals.pan.pl/Content/111826/PDF-MASTER/(52-3)221.pdf L2 - http://www.journals.pan.pl/Content/111826 PY - 2004 IS - No 3 EP - 230 KW - NMR KW - NOE path KW - RNA tertiary structure KW - evolutionary algorithm KW - branch-and-cut algorithm A1 - Błażewicz, J. A1 - Szachniuk, M. A1 - Wojtowicz, A. VL - vol. 52 DA - 2004 T1 - Evolutionary algorithm for a reconstruction of NOE paths in NMR spectra of RNA chains SP - 221 UR - http://www.journals.pan.pl/dlibra/publication/edition/111826 T2 - Bulletin of the Polish Academy of Sciences Technical Sciences ER -