The objective of this work is to present an energy analysis of different absorption refrigerating systems operating with diverse refrigerants. Also is applied the method of experimental design to optimize configurations proposed by the absorption pairs used and the operating conditions. Both acceptable coefficient of performance and low operating generator temperature are scrutinised. Therefore, a computer program is developed. An investigation of the thermodynamic properties is presented. Results show the coefficient of performance evolution versus respectively the evaporator temperature, temperature of condensation and generator temperature. A particular interest is devoted to the intermediate pressure effect on the performance of different systems. In order to better converge in the selection of the configuration and the refrigerant, which can ensure a high coefficient of performance associated to relatively low operating generator temperature the plan of experiments has been developed, taking in account all parameters influencing the system performance and the function of operating temperature. Results show that the refrigerating machine containing a compressor between the evaporator and the absorber has a coefficient of performance quite acceptable and that it can work at low generator temperature for about 60 ◦C and using the NH3/LiNO3 as refrigerant.