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Abstract

I n t r o d u c t i o n: Peripheral arterial occlusive disease (PAOD) is a disease with worldwide increasing occurrence. Diabetic patients are greatly exposed on the risk of PAOD and its complications. The aim of the study was to check the influence of preoperative HbA1C on the outcomes of patients with diabetes undergoing PAOD related endovascular treatment.

M a t e r i a l a n d Me t h o d s: The study was conducted among 59 patients with PAOD referred from the diabetic foot outpatient for endovascular treatment. They were included in one-year observation based on follow-up visits in 1, 3, 6 and 12 months after angioplasty and divided into 2 groups basing on their preoperative glycaemia. Th e clinical condition of the lower limbs was assessed by use of the Rutherford classification, ankle-brachial index (ABI) and toe-brachial index (TBI). Changes in patients’ quality of life (QoL) were also evaluated.

R e s u l t s: Reintervention within 12 months were less frequent in patients with HbA1C ≤8.0% than in HbA1C >8.0% patients (9.09% vs. 35.48%, p = 0.03). TBI of the treated limb was lower in patients with elevated than in patients with proper glycaemia at 6 month [0.2 (0.0–0.38) vs. 0.38 (0.31–0.46); p <0.008] and 12 month follow-up [0.17 (0.0–0.27) vs. 0.32 (0.25–0.38); p <0,001]. The rate of healed ulcerations after 6 months was higher in patients HbA1C ≤8.0% (45.0% vs. 16.13%; p = 0.02) and they had significantly greater improvement of QoL.

C on c l u s i o n: Results of this study shows that preoperative level of glycaemia is an important factor for long-term prognosis in diabetic patients with PAOD. Elevated HbA1C level decreases significantly long-term improvement of QoL in DM patients undergoing endovascular treatment.

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Authors and Affiliations

Agnieszka Wachsmann
Mikołaj Maga
Martyna Schönborn
Marta Olszewska
Mateusz Blukacz
Małgorzata Cebeńko
Agnieszka Trynkiewicz
Paweł Maga
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Abstract

Pelvic venous disorder (PeVD) is a prevalent chronic condition characterized by the presence of varicose veins in the pelvis, leading to the development of chronic pelvic pain. Despite the growing interest in assessing quality of life in PeVD, well-designed and validated disease-specific questionnaires are missing. The objective of this study was a linguistic and clinical validation of the Symptom Questionnaire (SQ) in a cohort of Polish females with pelvic vein incompetence. The Polish version of SQ was developed using a standardized validation process that involved a back-and- forth translation protocol.
A total of 58 female patients diagnosed with pelvic varicose veins, representing diverse educational back-grounds, participated in the study. Multiple issues were observed during linguistic validation, primarily originating from disparities between the Polish and British healthcare systems, as well as differing levels of sexual health education of those two populations. Cronbach α was calculated separately for each part of the questionnaire with results exceeded 0.6 for each section. Test-retest analysis indicated most Pearson correlation coefficients surpassing 0.70. The absolute agreement consistency between pretest and post- test measures, evaluated using the Intra Class Correlation (ICC), exceeded 0.8 in three sections and 0.7 in the remaining three sections.
However, the clinical validation failed due to the lack of standardized score calculation proposed by the authors of the questionnaire and inaccurately assigned values in the answer key for five questions. Consequently, the practical utility of SQ in daily clinical settings remains uncertain, highlighting the urgent need for the development of a new, user-friendly questionnaire specifically tailored to assess the quality of life in individuals with PeVD.
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Authors and Affiliations

Paulina Kłapacz
1 2
Mikołaj Maga
2 3
Łukasz Drelicharz
1 2
Jakub Krężel
2
Ewa Graczkowska
1
Kinga Krupa
1
Gabriela Trąd
1
Wojciech Maga
4
Łukasz Partyka
1 2
Paweł Maga
1 2

  1. Department of Angiology, Faculty of Medicine, Jagiellonian University Medical College, Kraków, Poland
  2. Clinical Department of Angiology, University Hospital in Kraków
  3. Department of Rehabilitation in Internal Medicine, Faculty of Health Sciences, Jagiellonian University Medical College, Kraków, Poland
  4. Prosthodontic and Orthodontic Department, Faculty of Medicine, Jagiellonian University Medical College, Kraków, Poland

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