Tool Like Receptors (TLR) are transmembrane proteins that play an important role in immune reactions associated with the recognition of pathogenic factors that cause infection. However, chronic infl ammatory conditions associated with the activation of these receptors create favorable conditions for the development of cancerous processes. Th e relationship between nuclear PPARγ receptors and TLR receptors is also important, whose role and importance in the process of carcinogenesis is the subject of various studies.