The aim of the experiments was to evaluate the effect of Sekator 6,25 WG used for broad leaved weeds control in winter and spring cereals. Sekator 6.25 WG herbicide is composed of iodosulfuron 1.25%, amidosulfuron 5% and mephenpyr diethyl 12.5%. The field trials were conducted over the period 1997-1999 at experimental station, which belonged to the Institute of Plant Protection. The results showed that Sekator 6,25 WG effectively controled Ga/ium aparine, Anthemis arvensis, Myosotis arvensis, Chenopodium album, Polygonum sp., Sinapis arvensis, Stel/aria media, Capsela bursa-pastoris, Thlaspi arvense and Lamium purpureum. The obtained yield of winter and spring cereals was increased by Sekator 6,25 WG application. Sekator 6,25 WG herbicide used in all experiments was safe for both winter and spring cereals.