A Novel Intelligent control of a Unified Power Quality Conditioner (UPQC) coupled with Photovoltaic (PV) system is proposed in this work. The utilization of a Re-lift Luo converter in conjunction with a Cascaded Artificial Neural Network (ANN) Maximum Power Point Tracking (MPPT) method facilitates the optimization of power extraction from PV sources. UPQC is made up of a series and shunt Active Power Filter (APF), where the former compensates source side voltage quality issues and the latter compensates the load side current quality issues. The PV along with a series and shunt APFs of the UPQC are linked to a common dc-bus and for regulating a dc-bus voltage a fuzzy tuned Adaptive PI controller is employed. Moreover, a harmonics free reference current is generated with the aid of CNN assisted dq theory in case of the shunt APF. The results obtained from MATLAB simulation.